Welcome to PoxFolds


Our PoxFolds Database gives interactive access to the complete predicted structures of Poxvirus proteomes. It will be updated with more viruses over time. We try filling a critical gap left by the absence of viral proteins in the EMBL/DeepMind AlphaFold database. As soon as more viruses are added, the table aims to group structurally similar proteins and homologs between viruses into one line.


Using FoldSeek, we have also generated protein structure groups that you can explore interactively at PoxClusters.


We hope that this resource will help you and the whole poxvirus research community!


PoxFolds is a project by the bosse lab and was generated by Timothy Soh, Sofia Ognibene, Robin Schaeper, Malte Kansy, and Jens Bosse.

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Structural similarity search identifies protein clusters.